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Biochemistry MPhil/PhD

The University of Worcester welcomes applications to undertake research towards MPhil and PhD degrees in Biochemistry.

Research at Worcester has grown significantly in the last 10 years as the University itself has expanded. As a research student you will join a vibrant student community in our Research School and become part of our dynamic research environment.

You will have the opportunity to be supervised by leading researchers in your field and take advantage of our rich Researcher Development programme which will help you to develop the skills and knowledge you need to complete your research degree but also enhance the skills you will need in any future career.


Factfile

Our MPhil/PhD research degree programme offers you:

Wide variety of research interests

The Institute of Science and the Environment has a strong mix of academics with a high degree of professional and personal experience, enabling you to get the most out of your programme. Our staff have expertise in:

  • Acute Myeloid Leukaemia
  • Human cell culture and analysis
  • Flow cytometry
  • Protein redox regulation
  • Cellular redox homeostasis
  • Cancer immunology and immunotherapy
  • Cancer cell signalling
  • Viral replication
  • Amino acid metabolism
  • Cell signalling (Receptor Tyrosine Kinase and cell-cell)
  • Ligand receptor interactions
  • Apoptosis
  • Genetics of plant breeding systems & hybridisation barriers
  • Molecular biology
  • Protein overexpression and purification
  • X-ray crystallography
  • Protein-protein interactions
  • Enzyme Kinetics       

Excellent supervision

Benefit from a professional and challenging relationship with your supervisory team, drawn from experienced academics working at the forefront of their disciplines.

Resources

Access to the University of Worcester’s virtual resources and its state of the art library facilities. The Biochemistry team at Worcester have an excellent range of resources available to support your learning and your research project, including:

  • ÄKTA pure protein purification system
  • BIORAD gravity chromatography systems
  • NanoDrop 2000c spectrophotometer
  • Gene expression systems including; bacterial, yeast, insect cell, mammalian cell and lenti-viral systems
  • GuavaCyte flow cytometer
  • Biological safety cabinet containment level-2
  • PCR
  • qRT-PCR
  • GC-MS/MS
  • LC-MS
  • Gel imaging
  • Various electrophoresis systems, including; SDS-PAGE, Western blot and immunoelectrophoresis
  • ELISA
  • Fluorescence microscopy
  • MiniMACS cell separation system
  • Large-scale microbial incubators
  • Human cell culture facility

Some of our current research students are exploring: The role of BCAT1 in the development and treatment of AML and monitoring intracellular and extracellular markers of oxidative stress in acute coronary syndrome.


How to apply

How to apply

Please make your application via our online application form. If you have any questions, please contact the Research School on 01905 542182 or research@worc.ac.uk

Before you submit a full application, please contact Dr David Storey (d.storey@worc.ac.uk) to discuss your research project and the availability of appropriate supervision.


Supervisors

Supervisors

Dr Alain Bueno
Expertise: dietary fats and the endocrine function of the adipose tissue and pancreas; diabetes and obesity as mild chronic inflammatory states and the role of endogenous antioxidants; cell membrane phospholipid composition in health and disease and its relation to nutritional status.

Dr Amy Cherry
Expertise: cancer cell signalling; viral Replication; protein expression and purification; crystallography; protein-protein interactions; molecular biology; gene cloning; mutagenesis; enzyme kinetics.

Dr Steven Coles
Expertise: Acute myeloid leukaemia (AML); protein and cellular redox regulation; AML/cancer immunology and immunotherapy; the role of metabolic processes in disease pathogenesis (branched-chain amino acid metabolism); cell signalling and apoptosis.

Dr Mike Wheeler
Expertise: cell-cell signalling in plants; plant receptor-ligand interactions; the biology and genetics of plant breeding systems; the genetics of natural hybridisation barriers in plants.


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